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Resample Web
A hosted web service for Aptamer Affinity Maturation library generation
Coded by Dr Andrew Brian Kinghorn
Use Resample Web
How Resample Works
Download Resample
Contact Us
Cite
Use Resample Web
To use Resample:
1) Input the aptamer family motif derived from a sequence alignment.
2) Select gap representation and aptamer type.
3) If base pairing information is known, check the 'Use structural constraints' checkbox and enter the base pair information in numerical form (ie. position numbers of pairing bases).
4) Hit the 'Run and save results' button.
Insert aptamer family motif here:
Show '-' for gaps in output
Remove replicates (show "-" must be unchecked)
Aptamer Type
DNA
RNA
Use structural constraints
Base pair 1)
=
Base pair 2)
=
Base pair 3)
=
Base pair 4)
=
Base pair 5)
=
Base pair 6)
=
Base pair 7)
=
Base pair 8)
=
Base pair 9)
=
Base pair 10)
=
How Resample Works
For details on Aptamer Affinity Maturation and how to use Resample please read our manuscript:
Kinghorn, Andrew B., Roderick M. Dirkzwager, Shaolin Liang, Yee-Wai Cheung, Lewis A. Fraser, Simon Chi-Chin Shiu, Marco SL Tang, and Julian A. Tanner. 'Aptamer Affinity Maturation by Resampling and Microarray Selection.' Analytical chemistry 88, no. 14 (2016): 6981-6985.
Download Resample
A stand alone version of Resample is availible upon request. Please email Dr Andrew Kinghorn for details -
Contact
Dr Andrew Brian Kinghorn -
Cite
Please cite our manuscript:
Kinghorn, Andrew B., Roderick M. Dirkzwager, Shaolin Liang, Yee-Wai Cheung, Lewis A. Fraser, Simon Chi-Chin Shiu, Marco SL Tang, and Julian A. Tanner. 'Aptamer Affinity Maturation by Resampling and Microarray Selection.' Analytical chemistry 88, no. 14 (2016): 6981-6985.
